Web9 feb. 2024 · Herein we show that telomere dysfunction in a human alveolar epithelial-like cell line leads to cellular senescence and an upregulation in transcriptional and proteomic SASP. Our results suggest that the consequences of telomere dysfunction may be species-specific and perhaps cell-type specific. Weband alveolar cells. These can be cultured as primary cells isolated from lung tissue e.g., primary HAE cells, differentiated pluripotent stem cells, or as immortalized or tumor cell lines such as Calu-3, a well-characterized human lung cancer cell line commonly used in models of human respiratory function, structure, and inflammatory responses1,2.

Surrogate infection model predicts optimal alveolar macrophage …

WebAlveolar epithelial cells undergo stretching during breathing and mechanical ventilation. Stretch can modify cell viscoelastic properties, which may compromise the balance of forces in the alveolar epithelium. We studied the viscoelasticity of . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on ... WebHGF is mitogenic for differentiated epithelial cells (e.g., hepatocytes, renal tubular cells, bronchial and alveolar epithelial cells, gastric epithelial cells, and keratinocytes, etc.), … kaitlin eastland campbell ca

Airway and alveolar epithelial cells in culture European …

WebAlveolar epithelial cell lines have been used since the late 80’s. A549 and NCI-H441 are still the most widely used human AEC cell lines in pharmaceutical research for lung … Web25 okt. 2016 · The alveolar epithelium is composed of type I and II pneumocytes. Equipped with a great number of epithelial junctions and ion-transporting proteins, they … WebPrimary human alveolar epithelial cells were immortalized by a novel regimen, grown as monolayers on permeable filter supports and characterized morphologically, … kaitlin elizabeth anne dawson