Spint1-as1
WebDec 1, 2024 · Afterwards, the implementation of mechanism assays help to verify that SPINT1-AS1 sequestered microRNA-433–3p (miR-433–3p) to regulate the expression of E2F transcription factor 3 (E2F3). Besides, E2F3 was validated to activate the transcription of SPINT1-AS1 in turn. Rescue experiments confirmed the functional influence of SPINT1 … WebA prognostic model was then established based on 14 immune-associated lncRNAs (LRRC8C-DT, AC021188.1, MALINC1, CCR5AS, EIF2AK3-DT, AC022306.2, AC242842.1, AL034376.1, AL662844.4, AC009065.3, AC099811.3, AC125807.2, SPINT1-AS1 and AC009495.2). Melanoma patients in the high-risk group had worse overall survival than …
Spint1-as1
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WebApr 13, 2024 · 结论 TMEM33经RNA干扰后，能明显抑制宫颈癌的细胞生长。. TMEM33可能通过影响宫颈癌细胞周期、调节细胞凋亡及细胞周期相关蛋白的表达来促进宫颈癌细胞的生长。. Abstract：Objective To explore the expression of transmembrane protein 33 (TMEM33) and its relationship with the prognosis in ... WebFeb 19, 2024 · SPINT1-AS1 is a Lapatinib sensitivity predictor, while GIHCG is a predictive molecule for Lapatinib resistance. Go to: Ethics Statement. The protocols used in this study were approved by Rui Jin Hospital Ethics Review Boards. Written informed consents were obtained from all human material donors in accordance with the Declaration of Helsinki.
WebNov 12, 2024 · The SPINT1-AS1 promoted the progression of breast cancer by regulating miR-let-7a/b/i-5p . In contrast, LINC00861 could inhibit cervical cancer's progression by competitively sponging miR‑513b‑5p . The LINC01094 promotes ccRCC development by miR-224-5p/CHSY1 or upregulating SLC2A3 via microRNA-184 [59, 60]. However, only a … WebResults: SPINT1-AS1 is up-regulated in the serum of breast cancer patients and breast cancer cell lines. The proliferation and migration ability of breast cancer cells were …
WebApr 26, 2024 · Consistently, SPINT1-AS1 knockdown abolished CRC tumorigenesis manifested as inhibited cell proliferation and autophagy, as well as promoted apoptosis. Interestingly, SPINT1 mRNA overexpression led to the same phenotypes as SPINT1-AS1 knockdown in CRC cells. In addition, exosome-mediated SPINT1-AS1 transfer promoted … WebOct 1, 2024 · In summary, the molecular axis of SPINT1-AS1/miR-433–3p/E2F3 forms a positive loop which might become a potential biomarker in CRC. Research article. Association of Interleukin-1β and Gene Polymorphisms with Liver Pathogenesis in Hepatitis B Virus Infection among Eastern Indian Population. Journal of Clinical and Experimental …
WebJul 10, 2024 · Dual luciferase reporter assay. Luciferase reporter gene vectors were constructed with SPINT1 mRNA 5′UTR sequences or mutant 5′UTR sequences in pGL3 …
WebSep 2, 2024 · Furthermore, SPINT1-AS1 was identified as a potential marker in the prognosis of colorectal cancer. High expression levels of SPINT1-AS1 was reported to correspond with a worse survival outcome 31 . bbc iplayer japanWebJan 1, 2024 · In addition, SPINT1-AS1 has been shown to be associated with hormone resistance. High levels of SPINT1-AS1 can be a biomarker sensitive to Lapatinib in NCI … day trip to tijuana from san diegobbc iplayer rupaulWebLncRNA SPINT1-AS1 is a Kunitz type 1 antisense RNA1, belonging to serine peptidase inhibitor. An increased expression of SPINT1-AS1 has been observed in colorectal cancer (Li C. et al., 2024). It is also the first time that lncRNA SPINT1-AS1 has been found regulating Lapatinib drug sensitivity on multiple cancer cells. day trip to tijuanaWebLncRNA SPINT1-AS1 is a Kunitz type 1 antisense RNA1, belonging to serine peptidase inhibitor. An increased expression of SPINT1-AS1 has been observed in colorectal cancer … day trip to mostar from dubrovnikWebShowing 25 of 57 results for SPINT1-AS1 Search Time: 0 ms in NEW (Click on the icon in the table below to see search hit context) Showing of 57 Results for SPINT1-AS1 Search Time: 0 ms. Export Show: Symbol Description Category UniProt ID GIFtS GC id Score; 1 ... day trip to zakopane from krakowWebJan 1, 2024 · Overexpression of SPINT1-AS1 is related to poor prognosis and is an independent prognostic factor for recurrence-free survival of patients with colorectal cancer. At the same time, SPINT1-AS1 can distinguish colorectal cancer patients from the control group with AUC = 0.865 . However, compared with adjacent tissues, SPINT1 and its sense … day trip from kona to maui